Epidermal growth factor receptor Antibody |
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F50599-0.4ML | NSJ Bioreagents | 0.4 ml | EUR 322.15 |
Description: EGFR is a receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [UniProt] |
Epidermal Growth Factor Receptor Antibody (HRP) |
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20-abx108222 | Abbexa |
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Epidermal Growth Factor Receptor Antibody (HRP) |
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abx108222-100g | Abbexa | 100 µg | EUR 362.5 |
Epidermal Growth Factor Receptor Antibody (HRP) |
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abx108222-20g | Abbexa | 20 µg | EUR 162.5 |
Epidermal Growth Factor Receptor Antibody (HRP) |
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abx108222-50g | Abbexa | 50 µg | EUR 250 |
Epidermal Growth Factor Receptor Antibody (FITC) |
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20-abx106803 | Abbexa |
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Epidermal growth factor receptor Antibody (EGFR) |
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F50597-0.08ML | NSJ Bioreagents | 0.08 ml | EUR 140.25 |
Description: The epidermal growth factor receptor is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer. |
Epidermal growth factor receptor Antibody (EGFR) |
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F50598-0.08ML | NSJ Bioreagents | 0.08 ml | EUR 140.25 |
Description: The epidermal growth factor receptor is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer. |
Epidermal growth factor receptor Antibody (EGFR) |
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F50599-0.08ML | NSJ Bioreagents | 0.08 ml | EUR 140.25 |
Description: EGFR is a receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling. Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin. [UniProt] |
Epidermal Growth Factor Receptor Antibody (FITC) |
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abx106803-100g | Abbexa | 100 µg | EUR 362.5 |
Epidermal Growth Factor Receptor Antibody (FITC) |
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abx106803-20g | Abbexa | 20 µg | EUR 162.5 |
Epidermal Growth Factor Receptor Antibody (FITC) |
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abx106803-50g | Abbexa | 50 µg | EUR 250 |
Epidermal Growth Factor Receptor Antibody (Biotin) |
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20-abx105384 | Abbexa |
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Epidermal Growth Factor Receptor Antibody (Biotin) |
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abx105384-100g | Abbexa | 100 µg | EUR 362.5 |
Epidermal Growth Factor Receptor Antibody (Biotin) |
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abx105384-20g | Abbexa | 20 µg | EUR 162.5 |