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Glucocorticoid receptor Thr524 phosphorylation by MINK1 induces interactions with 14-3-3 protein regulators

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Glucocorticoid receptor (GR) is a ligand-dependent transcription issue that performs a central position in irritation. GR exercise can also be modulated by way of protein-protein interactions, together with binding of 14-3-Three proteins induced by GR phosphorylation. However, the particular phosphorylation…