Synaptic transmission is mediated by the regulated exocytosis of synaptic vesicles. When the presynaptic membrane is depolarized by an incoming motion potential, voltage-gated calcium channels open, ensuing in the inflow of calcium ions that triggers the fusion of synaptic vesicles (SV) with the plasma membrane. SV are recycled by endocytosis. Phosphorylation of synaptic proteins performs a significant function in these processes, and a number of other research have proven that the synaptic phosphoproteome adjustments quickly in response to depolarization. However, it’s unclear which of these adjustments are immediately linked to SV-cycling and which could regulate different presynaptic features which are additionally managed by calcium-dependent kinases and phosphatases.
To deal with this query, we analyzed adjustments in the phosphoproteome utilizing rat synaptosomes in which exocytosis was blocked with botulinum neurotoxins (BoNTs) whereas depolarization-induced calcium inflow remained unchanged. BoNT-treatment considerably alters the response of the synaptic phoshoproteome to depolarization and outcomes in decreased phosphorylation ranges when in comparison with stimulation of synaptosomes by depolarization with KCl alone. We dissect the primary Ca2+-dependent phosphorylation from SV-cycling dependent phosphorylation and ensure an impact of such SV-cycling-dependent phosphorylation occasions on syntaxin-1a-T21/T23, Vamp2-S75, and cannabinoid receptor-1-S314/T322 on exo- and endocytosis in cultured hippocampal neurons.
We examined signaling variations between two co-stimulatory molecules, CD28 and ICAM-1 by analyzing transcription elements and proteins which are activated downstream of these co-stimulations. We noticed that FAST-1, an important protein in the TGFβ signaling pathway, was activated by solely ICAM-1 co-stimulation, and never by CD28. We additionally noticed that receptor tyrosine kinases Csk, Dtk, FGFR1 and ROR2 had been phosphorylated upon CD28 co-stimulation and IGF-1R, HGFR, MuSK and EphA8 had been phosphorylated upon ICAM-1 co-stimulation. Together, these findings recommend that these two co-stimulators induce the activation of completely different units of proteins, suggesting that every co-stimulatory molecule has its distinctive signaling profile.
Phosphorylation-regulated HMGA1a-P53 interplay unveils the operate of HMGA1a acidic tail phosphorylations through artificial proteins
As a typical member of intrinsically disordered proteins (IDPs), HMGA1a carries many post-translational modifications (PTMs). To examine the undefined operate of acidic tail phosphorylations, seven HMGA1a proteins with site-specific modification(s) had been chemically synthesized through Ser/Thr ligation. We discovered that the phosphorylations considerably inhibit HMGA1a-P53 interplay and the phosphorylations can induce conformational change of HMGA1a from an “open state” to a “shut state.” Notably, the positively charged lysine-arginine (KR) clusters are chargeable for modulating HMGA1a conformation through electrostatic interplay with the phosphorylated acidic tail.
Finally, we used an artificial protein-affinity purification mass spectrometry (SP-AP-MS) methodology to profile the particular interactors, which additional supported the operate of HMGA1a phosphorylation. Collectively, this examine highlights a mechanism for regulating IDPs’ conformation and performance by phosphorylation of non-protein-binding area and showcases that the protein chemical synthesis in mixture with mass spectrometry can function an environment friendly software to check the IDPs’ PTMs. SNTA1 protein ranges and phosphorylation standing had been decided in MDA-MB-231 cells publish jasplakinolide publicity utilizing western blotting and immunoprecipitation strategies respectively.
Lipopolysaccharide (LPS)-induced macrophage activation is a prototype of innate immune response. Although key effector proteins in LPS signaling pathway have been revealed, the map of dynamic protein interactions and phosphorylation in addition to the stoichiometry of protein complexes are missing. Here we current a dynamic map of protein interactions and phosphorylation in MyD88, TRAF6 and NEMO complexes obtained by SWATH-MS. The complete MS measurement results in quantification of as much as about 3,000 proteins throughout about 21-40 IP samples. We detected and quantified virtually all recognized interactors of MyD88, TRAF6 and NEMO.
By analyzing these quantitative information, we uncovered differential recruitment of IRAK household proteins to LPS-induced signaling complexes and decided the stoichiometry of the Myddosome complicated. In addition, quantitative phosphoproteomics evaluation recognized a quantity of unreported high-confidence phosphosites on the important thing proteins in LPS signaling pathway. Collectively, information of dynamic protein interactions and phosphorylation introduced by this examine might be a useful resource for additional examine of the LPS signaling pathway.
Jasplakinolide Attenuates Cell Migration by Impeding Alpha-1-syntrophin Protein Phosphorylation in Breast Cancer Cells
Alpha-1-syntrophin (SNTA1) is rising as a novel modulator of the actin cytoskeleton. SNTA1 binds to F-actin and regulates intracellular localization and exercise of varied actin organizing signaling molecules. Aberration in syntrophin signaling has been intently linked with deregulated progress linked to tumor growth/metastasis and its irregular over expression has been noticed in breast most cancers. In the current work the impact of jasplakinolide, an actin-binding cyclodepsipeptide, on the SNTA1 protein exercise and SNTA1 mediated downstream mobile occasions was studied in MDA-MB-231 breast most cancers cell line.
Prion Protein(PrP) Antibody |
48939 |
SAB |
100ul |
EUR 499 |
Prion Protein(PrP) Antibody |
48939-100ul |
SAB |
100ul |
EUR 399.6 |
Prion Protein(PrP) Antibody |
48939-50ul |
SAB |
50ul |
EUR 286.8 |
Prion Protein (PrP) Antibody |
abx120080-01ml |
Abbexa |
0.1 ml |
EUR 944.4 |
|
PrP Antibody / Prion protein |
RQ5040 |
NSJ Bioreagents |
100ul |
EUR 356.15 |
|
Description: The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. [RefSeq] |
PrP Antibody Prion protein |
R30892 |
NSJ Bioreagents |
100 ug |
EUR 356.15 |
|
Description: Prion protein, also known as CD230 and PrP, is a protein that in humans is encoded by the PRNP gene. Expression is predominantly in the nervous system but occurs to some degree in many other tissues throughout the body. Puckett et al.(1991)identified a RFLP with a high degree of heterozygosity in the 5-prime region of the PRNP gene, which might serve as a useful marker for the pter-p12 region of chromosome 20. PrP is associated with a variety of cognitive deficiencies and neurodegenerative diseases such as Creutzfeldt-Jakob disease, bovine spongiform encephalopathy, and kuru. The protein is highly conserved through mammals, lending credence to application of conclusions from test animals such as mice. Comparison between primates is especially similar, ranging from 92.9-99.6% similarity in amino acid sequences. |
Prion Protein (PRNP) Antibody |
abx431521-200ul |
Abbexa |
200 ul |
EUR 460.8 |
|
Prion Protein (PRNP) Antibody |
20-abx101113 |
Abbexa |
-
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|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Prion Protein (PRNP) Antibody |
20-abx101114 |
Abbexa |
-
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|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
Prion Protein (PRNP) Antibody |
20-abx174157 |
Abbexa |
-
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-
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|
|
|
Prion Protein (PRNP) Antibody |
abx120079-01ml |
Abbexa |
0.1 ml |
EUR 1779.6 |
|
Prion Protein (PRNP) Antibody |
20-abx114678 |
Abbexa |
-
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-
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|
|
|
Prion Protein (PRNP) Antibody |
abx002019-100l |
Abbexa |
100 µl |
EUR 387.5 |
Prion Protein (PRNP) Antibody |
abx002019-20l |
Abbexa |
20 µl |
EUR 175 |
Prion Protein (PRNP) Antibody |
abx002019-50l |
Abbexa |
50 µl |
EUR 275 |
Prion Protein (PRNP) Antibody |
abx227053-100g |
Abbexa |
100 µg |
EUR 325 |
Prion Protein (PRNP) Antibody |
abx114678-100l |
Abbexa |
100 µl |
EUR 612.5 |
Prion Protein (PRNP) Antibody |
abx139819-100g |
Abbexa |
100 µg |
EUR 425 |
Prion Protein (PRNP) Antibody |
abx101113-100l |
Abbexa |
100 µl |
EUR 262.5 |
Prion Protein (PRNP) Antibody |
abx101113-1ml |
Abbexa |
1 ml |
EUR 712.5 |
Prion Protein (PRNP) Antibody |
abx101113-200l |
Abbexa |
200 µl |
EUR 325 |
Prion Protein (PRNP) Antibody |
abx101114-100l |
Abbexa |
100 µl |
EUR 262.5 |
Prion Protein (PRNP) Antibody |
abx101114-1ml |
Abbexa |
1 ml |
EUR 725 |
Prion Protein (PRNP) Antibody |
abx101114-200l |
Abbexa |
200 µl |
EUR 337.5 |
Prion Protein (PRNP) Antibody |
abx174157-100l |
Abbexa |
100 µl |
EUR 750 |
Prion Protein (PRNP) Antibody |
abx174157-1ml |
Abbexa |
1 ml |
Ask for price |
Prion Protein (PRNP) Antibody |
abx174157-200l |
Abbexa |
200 µl |
Ask for price |
Prion Protein (PRNP) Antibody |
abx319681-100l |
Abbexa |
100 µl |
EUR 250 |
Prion Protein (PRNP) Antibody |
abx319681-50l |
Abbexa |
50 µl |
EUR 162.5 |
Prion Protein (PRNP) Antibody |
abx431521-200l |
Abbexa |
200 µl |
EUR 387.5 |
Prion Protein (PRNP) Antibody |
abx333875-100g |
Abbexa |
100 µg |
EUR 362.5 |
Prion Protein (PRNP) Antibody |
abx333875-20g |
Abbexa |
20 µg |
EUR 162.5 |
Prion Protein (PRNP) Antibody |
abx333875-50g |
Abbexa |
50 µg |
EUR 250 |
Prion Protein (PRNP) Antibody |
abx414218-200l |
Abbexa |
200 µl |
EUR 512.5 |
Prion Protein (PRNP) Antibody |
abx415314-200l |
Abbexa |
200 µl |
EUR 362.5 |
Prion Protein (PRNP) Antibody |
abx415315-200l |
Abbexa |
200 µl |
EUR 362.5 |
Prion Protein (PRNP) Antibody |
abx415316-200l |
Abbexa |
200 µl |
EUR 362.5 |
Prion Protein (PrPsc), Antibody |
GWB-8BFFBE |
GenWay Biotech |
0.1 mg Purified |
Ask for price |
Polyclonal Prion Protein Antibody |
APR12947G |
Leading Biology |
0.1ml |
EUR 580.8 |
Description: A polyclonal antibody raised in Chicken that recognizes and binds to Human Prion Protein . This antibody is tested and proven to work in the following applications: |
Prion Protein Polyclonal Antibody |
E-AB-92393-120uL |
Elabscience Biotech |
120uL |
EUR 320 |
|
Description: Unconjugated |
Prion Protein Polyclonal Antibody |
E-AB-92393-200uL |
Elabscience Biotech |
200uL |
EUR 530 |
|
Description: Unconjugated |
Prion Protein Polyclonal Antibody |
E-AB-92393-60uL |
Elabscience Biotech |
60uL |
EUR 200 |
|
Description: Unconjugated |
Prion Protein Polyclonal Antibody |
E-AB-92393-each |
Elabscience Biotech |
each |
Ask for price |
|
Description: Unconjugated |
Prion Protein 2 (PRND) Antibody |
20-abx114679 |
Abbexa |
-
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|
|
|
Prion Protein 2 (PRND) Antibody |
abx114679-100l |
Abbexa |
100 µl |
EUR 612.5 |
Prion Protein (PRNP) Antibody (HRP) |
abx319682-100l |
Abbexa |
100 µl |
EUR 250 |
Prion Protein (PRNP) Antibody (HRP) |
abx319682-50l |
Abbexa |
50 µl |
EUR 162.5 |
Prion Protein (PRNP) Antibody (HRP) |
abx336435-100g |
Abbexa |
100 µg |
EUR 362.5 |
Prion Protein (PRNP) Antibody (HRP) |
abx336435-20g |
Abbexa |
20 µg |
EUR 162.5 |
Prion Protein (PRNP) Antibody (HRP) |
abx336435-50g |
Abbexa |
50 µg |
EUR 250 |
Prion Protein (PRNP) Antibody Pair |
20-abx370619 |
Abbexa |
-
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-
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|
- 10 × 96 tests
- 5 × 96 tests
|
|
Prion Protein (PRNP) Antibody Pair |
20-abx370620 |
Abbexa |
-
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-
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|
- 10 × 96 tests
- 5 × 96 tests
|
|
Prion Protein (PRNP) Antibody Pair |
20-abx370621 |
Abbexa |
-
Ask for price
-
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|
- 10 × 96 tests
- 5 × 96 tests
|
|
Prion Protein (PRNP) Antibody (FITC) |
abx319683-100l |
Abbexa |
100 µl |
EUR 250 |
Prion Protein (PRNP) Antibody (FITC) |
abx319683-50l |
Abbexa |
50 µl |
EUR 162.5 |
Prion Protein (PRNP) Antibody Pair |
abx370619-100g |
Abbexa |
100 µg |
EUR 2550 |
Prion Protein (PRNP) Antibody Pair |
abx370619-50g |
Abbexa |
50 µg |
EUR 1575 |
Prion Protein (PRNP) Antibody Pair |
abx370620-100g |
Abbexa |
100 µg |
EUR 2312.5 |
Prion Protein (PRNP) Antibody Pair |
abx370620-50g |
Abbexa |
50 µg |
EUR 1437.5 |
Prion Protein (PRNP) Antibody Pair |
abx370621-100g |
Abbexa |
100 µg |
EUR 2250 |
Prion Protein (PRNP) Antibody Pair |
abx370621-50g |
Abbexa |
50 µg |
EUR 1400 |
Prion Protein (PRNP) Antibody (FITC) |
abx336436-100g |
Abbexa |
100 µg |
EUR 362.5 |
Prion Protein (PRNP) Antibody (FITC) |
abx336436-20g |
Abbexa |
20 µg |
EUR 162.5 |
Prion Protein (PRNP) Antibody (FITC) |
abx336436-50g |
Abbexa |
50 µg |
EUR 250 |
Major Prion Protein (PRNP) Antibody |
20-abx319681 |
Abbexa |
-
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|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Major Prion Protein (PRNP) Antibody |
20-abx333875 |
Abbexa |
-
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|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Major Prion Protein (PRNP) Antibody |
20-abx002019 |
Abbexa |
-
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|
- 100 ul
- 200 ul
- 20 ul
- 50 ul
|
|
Major Prion Protein (PRNP) Antibody |
abx140599-100g |
Abbexa |
100 µg |
EUR 425 |
Major Prion Protein (CD230) Antibody |
abx412470-01ml |
Abbexa |
0.1 ml |
EUR 844.8 |
|
Major Prion Protein (CD230) Antibody |
abx415314-01mg |
Abbexa |
0.1 mg |
EUR 543.6 |
|
Major Prion Protein (CD230) Antibody |
abx415315-01mg |
Abbexa |
0.1 mg |
EUR 543.6 |
|
Major Prion Protein (CD230) Antibody |
abx415316-01mg |
Abbexa |
0.1 mg |
EUR 543.6 |
|
Major Prion Protein (CD230) Antibody |
20-abx141693 |
Abbexa |
-
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-
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-
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|
|
|
Major Prion Protein (CD230) Antibody |
abx139819-01mg |
Abbexa |
0.1 mg |
EUR 610.8 |
|
Prion Protein (PRNP) Antibody (Biotin) |
abx319684-100l |
Abbexa |
100 µl |
EUR 250 |
Prion Protein (PRNP) Antibody (Biotin) |
abx319684-50l |
Abbexa |
50 µl |
EUR 162.5 |
Prion Protein (PRNP) Antibody (Biotin) |
abx336437-100g |
Abbexa |
100 µg |
EUR 362.5 |
Prion Protein (PRNP) Antibody (Biotin) |
abx336437-20g |
Abbexa |
20 µg |
EUR 162.5 |
Prion Protein (PRNP) Antibody (Biotin) |
abx336437-50g |
Abbexa |
50 µg |
EUR 250 |
Prion Protein(PrP) Conjugated Antibody |
C48939 |
SAB |
100ul |
EUR 476.4 |
Prion Protein Rabbit Monoclonal Antibody |
E10G21880 |
EnoGene |
100 μl |
EUR 275 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
Prion Protein Rabbit Polyclonal Antibody |
E10G22816 |
EnoGene |
100 μl |
EUR 275 |
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
Prion Protein-Interacting Protein (PRNIP) Antibody |
abx032619-400ul |
Abbexa |
400 ul |
EUR 627.6 |
|
Prion Protein-Interacting Protein (PRNIP) Antibody |
abx032619-80l |
Abbexa |
80 µl |
EUR 343.2 |
|
Prion Protein-Interacting Protein (PRNIP) Antibody |
abx032619-400l |
Abbexa |
400 µl |
EUR 518.75 |
Major Prion Protein (PRNP) Antibody (HRP) |
20-abx336435 |
Abbexa |
-
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|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Major Prion Protein (PRNP) Antibody (HRP) |
20-abx319682 |
Abbexa |
-
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|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Shadow Of Prion Protein (SPRN) Antibody |
20-abx339404 |
Abbexa |
-
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-
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|
|
|
Shadow of Prion Protein (SPRN) Antibody |
abx032300-400ul |
Abbexa |
400 ul |
EUR 627.6 |
|
Shadow of Prion Protein (SPRN) Antibody |
abx032300-80l |
Abbexa |
80 µl |
EUR 343.2 |
|
Shadow of Prion Protein (SPRN) Antibody |
abx032300-200l |
Abbexa |
200 µl |
EUR 518.75 |
Shadow of Prion Protein (SPRN) Antibody |
abx032300-50l |
Abbexa |
50 µl |
EUR 281.25 |
Shadow Of Prion Protein (SPRN) Antibody |
abx339404-100l |
Abbexa |
100 µl |
EUR 350 |
Shadow Of Prion Protein (SPRN) Antibody |
abx339404-50l |
Abbexa |
50 µl |
EUR 250 |
Major Prion Protein (PRNP) Antibody (FITC) |
20-abx336436 |
Abbexa |
-
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|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Major Prion Protein (PRNP) Antibody (FITC) |
20-abx319683 |
Abbexa |
-
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-
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|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Prion Protein recombinant monoclonal antibody |
A5436 |
Bimake |
100ul X 3 |
EUR 714 |
|
Description: A recombinant monoclonal antibody from rabbit against human Prion Protein for WB, IHC,ELISA |
Major Prion Protein (PRNP) Antibody (Biotin) |
20-abx336437 |
Abbexa |
-
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-
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|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Major Prion Protein (PRNP) Antibody (Biotin) |
20-abx319684 |
Abbexa |
-
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-
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|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
Polyclonal Antibody to Prion Protein (PRNP) |
PAB680Hu01 |
Cloud-Clone |
100ul |
EUR 232 |
|
Polyclonal Antibody to Prion Protein (PRNP) |
PAB680Hu02 |
Cloud-Clone |
100ul |
EUR 240 |
|
Polyclonal Antibody to Prion Protein (PRNP) |
PAB680Mu01 |
Cloud-Clone |
100ul |
EUR 239 |
|
Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse) |
4-PAB680Hu01 |
Cloud-Clone |
-
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|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP) |
Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat) |
4-PAB680Mu01 |
Cloud-Clone |
-
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|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP) |
Anti- Prion protease-resistant protein 27-30 (PrP27-30) N-Terminal Antibody |
GWB-8D9823 |
GenWay Biotech |
0.25 ml |
Ask for price |
Anti- Prion protease-resistant protein 27-30 (PrP27-30) N-Terminal Antibody |
GWB-92178F |
GenWay Biotech |
0.1 ml |
Ask for price |
Prion-Like Protein Doppel (PRND) Antibody |
20-abx322158 |
Abbexa |
-
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-
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|
|
|
Prion-Like Protein Doppel (PRND) Antibody |
20-abx320384 |
Abbexa |
-
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-
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|
|
|
Prion-Like Protein Doppel (Prnd) Antibody |
abx236794-100ug |
Abbexa |
100 ug |
EUR 661.2 |
|
Prion-Like Protein Doppel (PRND) Antibody |
20-abx006423 |
Abbexa |
-
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|
- 100 ul
- 200 ul
- 20 ul
- 50 ul
|
|
Prion-Like Protein Doppel (Prnd) Antibody |
abx236794-100g |
Abbexa |
100 µg |
EUR 350 |
Prion-Like Protein Doppel (PRND) Antibody |
abx320384-100l |
Abbexa |
100 µl |
EUR 350 |
Prion-Like Protein Doppel (PRND) Antibody |
abx320384-50l |
Abbexa |
50 µl |
EUR 237.5 |
Prion-Like Protein Doppel (PRND) Antibody |
abx322158-100g |
Abbexa |
100 µg |
EUR 350 |
Prion-Like Protein Doppel (PRND) Antibody |
abx322158-50g |
Abbexa |
50 µg |
EUR 237.5 |
Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse), PE |
4-PAB680Hu01-PE |
Cloud-Clone |
-
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|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP). This antibody is labeled with PE. |
Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat), PE |
4-PAB680Mu01-PE |
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Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP). This antibody is labeled with PE. |
Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse), APC |
4-PAB680Hu01-APC |
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Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP). This antibody is labeled with APC. |
Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse), Cy3 |
4-PAB680Hu01-Cy3 |
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Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP). This antibody is labeled with Cy3. |
Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse), HRP |
4-PAB680Hu01-HRP |
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- 100ul
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- 200ul
- 20ul
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Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP). This antibody is labeled with HRP. |
Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat), APC |
4-PAB680Mu01-APC |
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- 100ul
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- 1ml
- 200ul
- 20ul
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Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP). This antibody is labeled with APC. |
Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat), Cy3 |
4-PAB680Mu01-Cy3 |
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- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP). This antibody is labeled with Cy3. |
Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat), HRP |
4-PAB680Mu01-HRP |
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- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
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Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP). This antibody is labeled with HRP. |
Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse), FITC |
4-PAB680Hu01-FITC |
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- 100ul
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Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP). This antibody is labeled with FITC. |
Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat), FITC |
4-PAB680Mu01-FITC |
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- 100ul
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Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP). This antibody is labeled with FITC. |
Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse), Biotinylated |
4-PAB680Hu01-Biotin |
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Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP). This antibody is labeled with Biotin. |
Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat), Biotinylated |
4-PAB680Mu01-Biotin |
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Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP). This antibody is labeled with Biotin. |
Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse), APC-Cy7 |
4-PAB680Hu01-APC-Cy7 |
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- 100ul
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- 200ul
- 20ul
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Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP). This antibody is labeled with APC-Cy7. |
Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat), APC-Cy7 |
4-PAB680Mu01-APC-Cy7 |
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Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP). This antibody is labeled with APC-Cy7. |
Prion Protein (PrP) |
E8ET1610-27 |
EnoGene |
100ul |
EUR 275 |
Description: Available in various conjugation types. |
Prion Protein/CD230 |
CH23027 |
Neuromics |
200 ul |
EUR 553.2 |
Major prion protein |
AP79467 |
SAB |
1mg |
EUR 2640 |
|
Major prion protein |
AP79468 |
SAB |
1mg |
EUR 2640 |
|
Major prion protein |
AP86920 |
SAB |
1mg |
EUR 2640 |
|
Major prion protein |
AP87104 |
SAB |
1mg |
EUR 2640 |
|
Major prion protein |
AP87394 |
SAB |
1mg |
EUR 2640 |
|
Major prion protein |
AP87421 |
SAB |
1mg |
EUR 2640 |
|
Prion Protein Peptide |
45-123P |
ProSci |
0.1 mg |
EUR 405.6 |
Description: (IN) Prion Protein (143-153) Peptide |
Prion Protein (PRNP) Protein |
abx263341-10mg |
Abbexa |
10 mg |
EUR 325 |
Prion Protein (PRNP) Protein |
abx263341-25mg |
Abbexa |
25 mg |
EUR 1600 |
Prion Protein (PRNP) Protein |
abx263341-5mg |
Abbexa |
5 mg |
EUR 225 |
Cluster of Differentiation 230 Prion Protein Disease Form (CD230 PrPSc) Antibody |
abx414218-025mg |
Abbexa |
0.25 mg |
EUR 710.4 |
|
Prion protein PrP (PRNP) (93-109) mouse monoclonal antibody, clone 6D11, Purified |
AM05042PU-N |
Origene Technologies GmbH |
0.1 ml |
Ask for price |
Jasplakinolide therapy decreases proliferation of MDA-MB-231 cells in each dose and time dependent method. Results recommend that subtoxic doses of jasplakinolide induce morphological adjustments in MDA-MB-231 cells from flat spindle form adherent cells to spherical weakly adherent types. Mechanistically, jasplakinolide therapy was discovered to lower SNTA1 protein ranges and its tyrosine phosphorylation standing. Moreover, migratory potential of jasplakinolide handled cells was considerably inhibited in comparability to regulate cells. Our outcomes display that jasplakinolide inhibits cell migration by impairing SNTA1 functioning in breast most cancers cells.