Synaptic transmission is mediated by the regulated exocytosis of synaptic vesicles. When the presynaptic membrane is depolarized by an incoming motion potential, voltage-gated calcium channels open, ensuing in the inflow of calcium ions that triggers the fusion of synaptic vesicles (SV) with the plasma membrane. SV are recycled by endocytosis. Phosphorylation of synaptic proteins performs a significant function in these processes, and a number of other research have proven that the synaptic phosphoproteome adjustments quickly in response to depolarization. However, it’s unclear which of these adjustments are immediately linked to SV-cycling and which could regulate different presynaptic features which are additionally managed by calcium-dependent kinases and phosphatases.

To deal with this query, we analyzed adjustments in the phosphoproteome utilizing rat synaptosomes in which exocytosis was blocked with botulinum neurotoxins (BoNTs) whereas depolarization-induced calcium inflow remained unchanged. BoNT-treatment considerably alters the response of the synaptic phoshoproteome to depolarization and outcomes in decreased phosphorylation ranges when in comparison with stimulation of synaptosomes by depolarization with KCl alone. We dissect the primary Ca2+-dependent phosphorylation from SV-cycling dependent phosphorylation and ensure an impact of such SV-cycling-dependent phosphorylation occasions on syntaxin-1a-T21/T23, Vamp2-S75, and cannabinoid receptor-1-S314/T322 on exo- and endocytosis in cultured hippocampal neurons.

We examined signaling variations between two co-stimulatory molecules, CD28 and ICAM-1 by analyzing transcription elements and proteins which are activated downstream of these co-stimulations. We noticed that FAST-1, an important protein in the TGFβ signaling pathway, was activated by solely ICAM-1 co-stimulation, and never by CD28. We additionally noticed that receptor tyrosine kinases Csk, Dtk, FGFR1 and ROR2 had been phosphorylated upon CD28 co-stimulation and IGF-1R, HGFR, MuSK and EphA8 had been phosphorylated upon ICAM-1 co-stimulation. Together, these findings recommend that these two co-stimulators induce the activation of completely different units of proteins, suggesting that every co-stimulatory molecule has its distinctive signaling profile.

Phosphorylation-regulated HMGA1a-P53 interplay unveils the operate of HMGA1a acidic tail phosphorylations through artificial proteins

As a typical member of intrinsically disordered proteins (IDPs), HMGA1a carries many post-translational modifications (PTMs). To examine the undefined operate of acidic tail phosphorylations, seven HMGA1a proteins with site-specific modification(s) had been chemically synthesized through Ser/Thr ligation. We discovered that the phosphorylations considerably inhibit HMGA1a-P53 interplay and the phosphorylations can induce conformational change of HMGA1a from an “open state” to a “shut state.” Notably, the positively charged lysine-arginine (KR) clusters are chargeable for modulating HMGA1a conformation through electrostatic interplay with the phosphorylated acidic tail.

Finally, we used an artificial protein-affinity purification mass spectrometry (SP-AP-MS) methodology to profile the particular interactors, which additional supported the operate of HMGA1a phosphorylation. Collectively, this examine highlights a mechanism for regulating IDPs’ conformation and performance by phosphorylation of non-protein-binding area and showcases that the protein chemical synthesis in mixture with mass spectrometry can function an environment friendly software to check the IDPs’ PTMs. SNTA1 protein ranges and phosphorylation standing had been decided in MDA-MB-231 cells publish jasplakinolide publicity utilizing western blotting and immunoprecipitation strategies respectively.

Lipopolysaccharide (LPS)-induced macrophage activation is a prototype of innate immune response. Although key effector proteins in LPS signaling pathway have been revealed, the map of dynamic protein interactions and phosphorylation in addition to the stoichiometry of protein complexes are missing. Here we current a dynamic map of protein interactions and phosphorylation in MyD88, TRAF6 and NEMO complexes obtained by SWATH-MS. The complete MS measurement results in quantification of as much as about 3,000 proteins throughout about 21-40 IP samples. We detected and quantified virtually all recognized interactors of MyD88, TRAF6 and NEMO.

By analyzing these quantitative information, we uncovered differential recruitment of IRAK household proteins to LPS-induced signaling complexes and decided the stoichiometry of the Myddosome complicated. In addition, quantitative phosphoproteomics evaluation recognized a quantity of unreported high-confidence phosphosites on the important thing proteins in LPS signaling pathway. Collectively, information of dynamic protein interactions and phosphorylation introduced by this examine might be a useful resource for additional examine of the LPS signaling pathway.

Protein phosphorylation in depolarized synaptosomes: Dissecting primary effects of calcium from synaptic vesicle cycling

Jasplakinolide Attenuates Cell Migration by Impeding Alpha-1-syntrophin Protein Phosphorylation in Breast Cancer Cells

Alpha-1-syntrophin (SNTA1) is rising as a novel modulator of the actin cytoskeleton. SNTA1 binds to F-actin and regulates intracellular localization and exercise of varied actin organizing signaling molecules. Aberration in syntrophin signaling has been intently linked with deregulated progress linked to tumor growth/metastasis and its irregular over expression has been noticed in breast most cancers. In the current work the impact of jasplakinolide, an actin-binding cyclodepsipeptide, on the SNTA1 protein exercise and SNTA1 mediated downstream mobile occasions was studied in MDA-MB-231 breast most cancers cell line.

Anti-Prion

DB-080-0.05 50 μl
EUR 282

Anti-Prion

DB-080-0.1 100 μl
EUR 443

Anti-Prion

DB-081-0.05 50 μl
EUR 282

Anti-Prion

DB-081-0.1 100 μl
EUR 443

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 349

Anti-Prion protein PrP/PRNP Antibody

PA1794 100ug/vial
EUR 294

Anti-Prion protein PrP/PRNP Antibody

PA1795 100ug/vial
EUR 334

Anti-Prion Protein Rabbit Monoclonal Antibody

M02447 100ug/vial
EUR 397
Description: Rabbit Monoclonal Prion Protein Antibody. Validated in Flow Cytometry, IF, IHC, ICC, WB and tested in Human, Mouse, Rat.

Anti-Prion protein PrP/PRNP Antibody

PB9783 100ug/vial
EUR 334

Anti-Prion Protein (143-153) antibody

STJ70951 100 µg
EUR 359

anti-Prion protein antibody mouse monoclonal (7A1)

65-903 50ug
EUR 296
Description: The anti-Prion protein antibody mouse monoclonal (7A1) is available in Europe and for worldwide shipping via Gentaur.

Prion Protein(PrP) Antibody

48939-100ul 100ul
EUR 333

Prion Protein(PrP) Antibody

48939-50ul 50ul
EUR 239

Prion Protein (PRNP) Antibody

20-abx101113
  • EUR 411.00
  • EUR 133.00
  • EUR 1149.00
  • EUR 565.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Prion Protein (PRNP) Antibody

20-abx101114
  • EUR 425.00
  • EUR 133.00
  • EUR 1177.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Prion Protein (PRNP) Antibody

20-abx114678
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul
  • Shipped within 5-10 working days.

Prion Protein (PRNP) Antibody

abx120079-01ml 0.1 ml
EUR 1483
  • Shipped within 5-10 working days.

Prion Protein (PrP) Antibody

abx120080-01ml 0.1 ml
EUR 787
  • Shipped within 5-10 working days.

Prion Protein (PRNP) Antibody

20-abx174157
  • EUR 815.00
  • EUR 425.00
  • 1 mg
  • 200 ug
  • Please enquire.

Polyclonal Prion Protein Antibody

APR12947G 0.1ml
EUR 484
Description: A polyclonal antibody raised in Chicken that recognizes and binds to Human Prion Protein . This antibody is tested and proven to work in the following applications:

Prion Protein (PRNP) Antibody

abx431521-200ul 200 ul
EUR 384
  • Shipped within 1-3 working days.

anti-Prion protein antibody mouse monoclonal (2C5-5)

65-901 50ug
EUR 296
Description: The anti-Prion protein antibody mouse monoclonal (2C5-5) is available in Europe and for worldwide shipping via Gentaur.

Polyclonal Goat Anti-Prion Protein (143-153) Antibody

AMM05951G 0.1 mg
EUR 484
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human Goat Anti-Prion Protein (143-153) . This antibody is tested and proven to work in the following applications:

Prion Protein/CD230

CH23027 200 ul
EUR 461

Anti-Hu CD230 / Prion Purified

11-593-C025 0.025 mg
EUR 149

Anti-Hu CD230 / Prion Purified

11-593-C100 0.1 mg
EUR 258

Prion Protein 2 (PRND) Antibody

20-abx114679
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul
  • Shipped within 5-10 working days.

Major Prion Protein (CD230) Antibody

abx139819-01mg 0.1 mg
EUR 509
  • Shipped within 5-12 working days.

Major Prion Protein (CD230) Antibody

20-abx141693
  • EUR 370.00
  • EUR 606.00
  • EUR 300.00
  • 100 ul
  • 200 ul
  • 50 ul
  • Shipped within 5-10 working days.

Prion Protein(PrP) Conjugated Antibody

C48939 100ul
EUR 397

Major Prion Protein (CD230) Antibody

abx412470-01ml 0.1 ml
EUR 704
  • Shipped within 1 week.

Major Prion Protein (PRNP) Antibody

20-abx319681
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Major Prion Protein (PRNP) Antibody

20-abx333875
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Prion Protein (PRNP) Antibody Pair

20-abx370619
  • EUR 1887.00
  • EUR 1191.00
  • 10 × 96 tests
  • 5 × 96 tests
  • Shipped within 5-15 working days.

Prion Protein (PRNP) Antibody Pair

20-abx370620
  • EUR 1706.00
  • EUR 1094.00
  • 10 × 96 tests
  • 5 × 96 tests
  • Shipped within 5-15 working days.

Prion Protein (PRNP) Antibody Pair

20-abx370621
  • EUR 1664.00
  • EUR 1066.00
  • 10 × 96 tests
  • 5 × 96 tests
  • Shipped within 5-15 working days.

Major Prion Protein (CD230) Antibody

abx415314-01mg 0.1 mg
EUR 453
  • Shipped within 1 week.

Major Prion Protein (CD230) Antibody

abx415315-01mg 0.1 mg
EUR 453
  • Shipped within 1 week.

Major Prion Protein (CD230) Antibody

abx415316-01mg 0.1 mg
EUR 453
  • Shipped within 1 week.

Prion Protein recombinant monoclonal antibody

A5436 100ul X 3
EUR 595
  • Comparisons between Mnoclonal, Polyclonal and Recombinant antibodies and their benefits: Regular monoclonal antibodies have higher purity, better specificity and less lot-to-lot variations than polyclonal antibodies. Recombinant antibodies, however,
  • Show more
Description: A recombinant monoclonal antibody from rabbit against human Prion Protein for WB, IHC,ELISA

Major Prion Protein (PRNP) Antibody

20-abx002019
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
  • Shipped within 5-10 working days.

Prion Protein-Interacting Protein (PRNIP) Antibody

abx032619-400ul 400 ul
EUR 523
  • Shipped within 5-10 working days.

Prion Protein-Interacting Protein (PRNIP) Antibody

abx032619-80l 80 µl
EUR 286
  • Shipped within 5-10 working days.

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 280

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 280

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 280

Prion Protein, RNA Aptamer

AR-316-U Custom Ask for price

Recombinant Prion Protein (PRNP)

4-RPB680Hu01
  • EUR 490.66
  • EUR 234.00
  • EUR 1564.96
  • EUR 588.32
  • EUR 1076.64
  • EUR 391.00
  • EUR 3762.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P04156
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 26.6kDa
  • Isoelectric Point: 9.5
Description: Recombinant Human Prion Protein expressed in: E.coli

Recombinant Prion Protein (PRNP)

4-RPB680Mu01
  • EUR 512.16
  • EUR 240.00
  • EUR 1645.60
  • EUR 615.20
  • EUR 1130.40
  • EUR 406.00
  • EUR 3964.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P04925
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 26.8kDa
  • Isoelectric Point: 9.6
Description: Recombinant Mouse Prion Protein expressed in: E.coli

Prion-Like Protein Doppel (PRND) Antibody

20-abx006423
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
  • Shipped within 5-10 working days.

Shadow of Prion Protein (SPRN) Antibody

abx032300-400ul 400 ul
EUR 523
  • Shipped within 5-10 working days.

Shadow of Prion Protein (SPRN) Antibody

abx032300-80l 80 µl
EUR 286
  • Shipped within 5-10 working days.

Shadow Of Prion Protein (SPRN) Antibody

20-abx339404
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Major Prion Protein (PRNP) Antibody (HRP)

20-abx319682
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Major Prion Protein (PRNP) Antibody (FITC)

20-abx319683
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Major Prion Protein (PRNP) Antibody (Biotin)

20-abx319684
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Prion-Like Protein Doppel (PRND) Antibody

20-abx320384
  • EUR 300.00
  • EUR 244.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Prion-Like Protein Doppel (Prnd) Antibody

abx236794-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

Major Prion Protein (PRNP) Antibody (HRP)

20-abx336435
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Major Prion Protein (PRNP) Antibody (FITC)

20-abx336436
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Major Prion Protein (PRNP) Antibody (Biotin)

20-abx336437
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Prion-Like Protein Doppel (PRND) Antibody

20-abx322158
  • EUR 300.00
  • EUR 244.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Mouse Prion Protein (PRNP) Protein

20-abx068666
  • EUR 718.00
  • EUR 286.00
  • EUR 2221.00
  • EUR 857.00
  • EUR 509.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Human Prion Protein (PRNP) Protein

20-abx068667
  • EUR 690.00
  • EUR 286.00
  • EUR 2110.00
  • EUR 815.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Major Prion Protein (PRNP) Protein

20-abx263341
  • EUR 1609.00
  • EUR 328.00
  • EUR 230.00
  • 100 ug
  • 10 ug
  • 2 µg
  • Shipped within 5-10 working days.

Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse)

4-PAB680Hu01
  • EUR 239.00
  • EUR 2391.00
  • EUR 598.00
  • EUR 299.00
  • EUR 211.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PRNP (Lys23~Ser230)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP)

Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat)

4-PAB680Mu01
  • EUR 243.00
  • EUR 2457.00
  • EUR 613.00
  • EUR 305.00
  • EUR 212.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PRNP (Lys23~Ser230)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP)

Rat Major prion protein (Prnp)

1-CSB-EP018739RA
  • EUR 505.00
  • EUR 265.00
  • EUR 1827.00
  • EUR 766.00
  • EUR 1218.00
  • EUR 335.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 26.3 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Rat Major prion protein(Prnp) expressed in E.coli

Rat Major prion protein (Prnp)

1-CSB-YP018739RA
  • EUR 504.00
  • EUR 265.00
  • EUR 1832.00
  • EUR 763.00
  • EUR 1216.00
  • EUR 334.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 24.3 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Rat Major prion protein(Prnp) expressed in Yeast

Prion Protein 106-126 (human)

B5433-.5 500 µg
EUR 251

Prion Protein 106-126 (human)

B5433-1 1 mg
EUR 373

Prion Protein (106-126) (human)

H-1566.0500 0.5mg
EUR 273
Description: Sum Formula: C80H138N26O24S2; CAS# [148439-49-0] net

Prion Protein (106-126) (human)

H-1566.1000 1.0mg
EUR 418
Description: Sum Formula: C80H138N26O24S2; CAS# [148439-49-0] net

Prion Protein (118-135) (human)

H-4206.0001 1.0mg
EUR 576
Description: Sum Formula: C68H112N18O22S2; CAS# [202121-03-7] net

Prion Protein (118-135) (human)

H-4206.0005 5.0mg
EUR 2207
Description: Sum Formula: C68H112N18O22S2; CAS# [202121-03-7] net

Monoclonal Prion Antibody, Clone: EP1802Y

APR12946G 0.1ml
EUR 528
Description: A Monoclonal antibody against Human Prion. The antibodies are raised in Rabbit and are from clone EP1802Y. This antibody is applicable in WB and IHC

Prion-Like Protein Doppel (PRND) Protein

20-abx263269
  • EUR 1609.00
  • EUR 328.00
  • EUR 230.00
  • 100 ug
  • 10 ug
  • 2 µg
  • Shipped within 5-10 working days.

PRND Prion Protein 2Human Recombinant Protein

PROTQ9UKY0 Regular: 10ug
EUR 317
Description: PRND Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 149 amino acids (27-152a.a) and having a molecular mass of 58.5kDa. PRND is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

PRNP Prion Protein Human Recombinant Protein

PROTP04156 Regular: 10ug
EUR 317
Description: PRNP Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 229 amino acids (23-230a.a) and having a molecular mass of 25kDa. GOSR2 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse), APC

4-PAB680Hu01-APC
  • EUR 333.00
  • EUR 3113.00
  • EUR 872.00
  • EUR 423.00
  • EUR 215.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PRNP (Lys23~Ser230)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP). This antibody is labeled with APC.

Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse), Biotinylated

4-PAB680Hu01-Biotin
  • EUR 303.00
  • EUR 2341.00
  • EUR 697.00
  • EUR 369.00
  • EUR 216.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PRNP (Lys23~Ser230)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP). This antibody is labeled with Biotin.

Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse), Cy3

4-PAB680Hu01-Cy3
  • EUR 403.00
  • EUR 4109.00
  • EUR 1121.00
  • EUR 523.00
  • EUR 245.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PRNP (Lys23~Ser230)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP). This antibody is labeled with Cy3.

Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse), FITC

4-PAB680Hu01-FITC
  • EUR 287.00
  • EUR 2510.00
  • EUR 717.00
  • EUR 359.00
  • EUR 192.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PRNP (Lys23~Ser230)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP). This antibody is labeled with FITC.

Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse), HRP

4-PAB680Hu01-HRP
  • EUR 305.00
  • EUR 2714.00
  • EUR 772.00
  • EUR 383.00
  • EUR 203.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PRNP (Lys23~Ser230)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP). This antibody is labeled with HRP.

Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse), PE

4-PAB680Hu01-PE
  • EUR 287.00
  • EUR 2510.00
  • EUR 717.00
  • EUR 359.00
  • EUR 192.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PRNP (Lys23~Ser230)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP). This antibody is labeled with PE.

Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat), APC

4-PAB680Mu01-APC
  • EUR 340.00
  • EUR 3203.00
  • EUR 894.00
  • EUR 432.00
  • EUR 217.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PRNP (Lys23~Ser230)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP). This antibody is labeled with APC.

Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat), Biotinylated

4-PAB680Mu01-Biotin
  • EUR 307.00
  • EUR 2407.00
  • EUR 714.00
  • EUR 375.00
  • EUR 217.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PRNP (Lys23~Ser230)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP). This antibody is labeled with Biotin.

Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat), Cy3

4-PAB680Mu01-Cy3
  • EUR 411.00
  • EUR 4229.00
  • EUR 1151.00
  • EUR 535.00
  • EUR 248.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PRNP (Lys23~Ser230)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP). This antibody is labeled with Cy3.

Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat), FITC

4-PAB680Mu01-FITC
  • EUR 292.00
  • EUR 2582.00
  • EUR 735.00
  • EUR 366.00
  • EUR 194.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PRNP (Lys23~Ser230)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP). This antibody is labeled with FITC.

Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat), HRP

4-PAB680Mu01-HRP
  • EUR 311.00
  • EUR 2792.00
  • EUR 791.00
  • EUR 391.00
  • EUR 205.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PRNP (Lys23~Ser230)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP). This antibody is labeled with HRP.

Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat), PE

4-PAB680Mu01-PE
  • EUR 292.00
  • EUR 2582.00
  • EUR 735.00
  • EUR 366.00
  • EUR 194.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PRNP (Lys23~Ser230)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP). This antibody is labeled with PE.

Human Prion Protein (PRNP) ELISA Kit

DLR-PRNP-Hu-48T 48T
EUR 498
  • Should the Human Prion Protein (PRNP) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Prion Protein (PRNP) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

DLR-PRNP-Hu-96T 96T
EUR 647
  • Should the Human Prion Protein (PRNP) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Prion Protein (PRNP) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

DLR-PRNP-Mu-48T 48T
EUR 508
  • Should the Mouse Prion Protein (PRNP) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Prion Protein (PRNP) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

DLR-PRNP-Mu-96T 96T
EUR 661
  • Should the Mouse Prion Protein (PRNP) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Prion Protein (PRNP) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

20-abx156738
  • EUR 7112.00
  • EUR 3792.00
  • EUR 879.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.

Mouse Prion Protein (PRNP) ELISA Kit

20-abx156832
  • EUR 7237.00
  • EUR 3855.00
  • EUR 895.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.

Mouse Prion Protein (PRNP) ELISA Kit

abx255159-96tests 96 tests
EUR 746
  • Shipped within 5-12 working days.
Jasplakinolide therapy decreases proliferation of MDA-MB-231 cells in each dose and time dependent method. Results recommend that subtoxic doses of jasplakinolide induce morphological adjustments in MDA-MB-231 cells from flat spindle form adherent cells to spherical weakly adherent types. Mechanistically, jasplakinolide therapy was discovered to lower SNTA1 protein ranges and its tyrosine phosphorylation standing. Moreover, migratory potential of jasplakinolide handled cells was considerably inhibited in comparability to regulate cells. Our outcomes display that jasplakinolide inhibits cell migration by impairing SNTA1 functioning in breast most cancers cells.
Protein phosphorylation in depolarized synaptosomes: Dissecting primary effects of calcium from synaptic vesicle cycling
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